Our overall research interests center on how transporter-mediated zinc and manganese mobilization function to regulate diverse cellular processes in health and disease.

Research Focus

The Aydemir Lab investigates how essential micronutrients—particularly zinc and manganese—regulate critical cellular processes and maintain human health. Through preclinical animal models and ex vivo organoid cultures, we study how the Solute Carrier (SLC) family of metal transporters facilitates micronutrient functions across tissues, organs, and cells.

Our approach integrates multiple scientific disciplines, including:

• Advanced biochemistry techniques

• Molecular biology methods

• Cutting-edge nutritional genomics

• State-of-the-art metallomics analysis using Microwave Plasma Atomic Emission Spectroscopy (MP-AES)

Our research explores interactions between:

• Gene-micronutrient

• Macronutrient-micronutrient

• Disease-micronutrient

Current Research Priorities

• Understanding zinc and manganese transport dynamics in health and disease

• Investigating zinc-mediated interactions between host systems and gut microbiome

• Examining how these processes influence multiple organ systems in chronic inflammatory conditions and metabolic disorders