placeholder

Saurabh

Mehta

Associate Professor of Global Health, Epidemiology, and Nutrition
Division of Nutritional Sciences
Office

314 Savage Hall

Biography

I am a physician and an epidemiologist with expertise in infectious disease, nutrition, maternal and child health, and diagnostics. The central theme of my research is the interplay between nutrition and infection, including facilitating field-friendly assessment for both, and elucidating how nutrition can be used as a modifiable risk factor for infections and associated outcomes, often in the context of pregnancy and early childhood. This is achieved through a combination of active surveillance programs, invention of point-of-care diagnostics for nutrition and infection, and randomized controlled trials primarily in resource-limited settings in India, sub-Saharan Africa, and Latin America. 

I am currently the principal investigator on two large randomized efficacy trials to determine the effect of delivering micronutrients through biofortified crops on nutrition and immune function in infants in India. A major emphasis in these studies is to understand how diet may modulate the gut microbiome early in life in collaboration with the Rob Knight Lab in UCSD. 

David Erickson and I are also the co-inventors of the Cornell NutriPhone and FeverPhone, a NSF- and NIH-funded platform for point-of-care diagnosis of nutritional status and infections. In Ecuador, I have been focusing on neglected tropical diseases such as dengue virus infection and am currently the principal investigator on an NIH R01 focusing on the development of FeverPhone for differential diagnosis of acute febrile illnesses. 

I also serve as a consultant to the World Health Organization on topics such as tuberculosis, nutrition, and diagnostic test accuracy. This has also involved recently serving as the external expert on Emergency Guideline Development Meeting for Zika virus and publishing the first systematic review on mother to child transmission of Zika virus, which served as the basis for the current guidelines on this topic. This is now being updated to include other infections such as Ebola virus disease and will be released in December 2019/Spring 2020. 

 

The Mehta Research Group primarily works in India in the states of Maharashtra and Andhra Pradesh and coastal Ecuador. Our focus is on vulnerable populations including mothers and children, and those suffering from infectious diseases such as HIV infection, Tuberculosis, Dengue virus infection, Zika virus infection, and Malaria.

The aspirational goal and guiding principle of our team is to deliver community health care in the community itself to either prevent poor health outcomes and/or reduce their severity/impact. Consequently, our research is on a) identifying risk factors that predict poor health in our communities as early as possible through active surveillance; b) inventing field-friendly devices such as the Cornell NutriPhone and FeverPhone to enable community-level or point-of-need diagnoses; and c) intervening to modify the identified risk factors mainly through sustainable interventions.

Given that a) the majority of the world is either over- or under-nourished; and b) diet and nutrition-related factors represent the largest proportion of risk factors for global mortality and morbidity, we often use nutritional interventions to modify the risk of adverse health outcomes in our research. Further, we examine the mechanistic linkages between nutrition and health - for example, we recently concluded a randomized trial of iron-rich pearl millet among children in urban slums of Mumbai to determine its effect on growth and immune function, among other outcomes, and are also assessing how this effect may be modified by the gut microbiome’s composition and function. 

 

Peer Reviewed Publications 

  1. Wang R, Vemulapati S, Westblade LF, Glesby MJ, Mehta S, Erickson D. cAST: Capillary-Based Platform for Real-Time Phenotypic Antimicrobial Susceptibility Testing. Analytical Chemistry2020 Jan 16;. doi: 10.1021/ acs.analchem.9b04991. [Epub ahead of print] PubMed PMID: 31944675. 
  2. Finkelstein JL, Colt S, Layden AJ, Krisher JT, Stewart-Ibarra AM, Polhemus M, Beltrán-Ayala E, Tedesco JM, Cárdenas WB, Endy T, Mehta S. Micronutrients, Immunological Parameters, and Dengue Virus Infection in Coastal Ecuador: A Nested Case-Control Study in an Infectious Disease Surveillance Program. Journal of Infectious Diseases2020 Jan 1;221(1):91-101. doi: 10.1093/infdis/jiz427. PubMed PMID: 31428794; PubMed Central PMCID: PMC6910873.
  3. Nevins JE, Venkatramanan S, Mehta S, Haas JD. Predicting potential to benefit from an iron intervention: a randomized controlled trial of double-fortified salt in female Indian tea pluckers. Public Health Nutrition2019 Dec;22(18):3416-3425. doi: 10.1017/S1368980019001800. Epub 2019 Jul 25. PubMed PMID: 31342886; PubMed Central PMCID: PMC6891141. 
  4. *Gannon BM, Glesby MJ, Finkelstein JL, Raj T, Erickson D, Mehta S. A point-of-care assay for alpha-1-acid glycoprotein as a diagnostic tool for rapid, mobile-based determination of inflammation. Current Research in Biotechnology, 2019.doi:10.1016/j.crbiot.2019.09.002.
  5. Gomes F, Bourassa MW, Adu-Afarwuah S, Ajello C, Bhutta ZA, Black R, Catarino E, Chowdhury R, Dalmiya N, Dwarkanath P, Engle-Stone R, Gernand AD, Goudet S, Hoddinott J, Kaestel P, Manger MS, McDonald CM, Mehta S, Moore SE, Neufeld LM, Osendarp S, Ramachandran P, Rasmussen KM, Stewart C, Sudfeld C, West K, Bergeron G. Setting research priorities on multiple micronutrient supplementation in pregnancy. Annals of the New York Academy of Sciences2019 Nov 6;. doi: 10.1111/nyas.14267. [Epub ahead of print] PubMed PMID: 31696532.
  6. Ahmad R, Xie L, Pyle M, Suarez MF, Broger T, Steinberg D, Ame SM, Lucero MG, Szucs MJ, MacMullan M, Berven FS, Dutta A, Sanvictores DM, Tallo VL, Bencher R, Eisinger DP, Dhingra U, Deb S, Ali SM, Mehta S, Fawzi WW, Riley ID, Sazawal S, Premji Z, Black R, Murray CJL, Rodriguez B, Carr SA, Walt DR, Gillette MA. A rapid triage test for active pulmonary tuberculosis in adult patients with persistent cough. Science Translational Medicine2019 Oct 23;11(515). doi: 10.1126/scitranslmed.aaw8287. PubMed PMID: 31645455.
  7. *Kim J, Cao XE, Finkelstein JL, Cárdenas WB, Erickson D, Mehta S.A two-colour multiplexed lateral flow immunoassay system to differentially detect human malaria species on a single test line. Malaria Journal2019 Sep 18;18(1):313. doi: 10.1186/s12936-019-2957-x. PubMed PMID: 31533756.
  8. Dwarkanath P, Vinotha P, Thomas T, Joseph S, Thomas A, Shirley G, Sheela CN, Mehta S, Kurpad AV. Relationship of Early Vitamin D Concentrations and Gestational Diabetes Mellitus in Indian Pregnant Women. Frontiers in Nutrition2019;6:116. doi: 10.3389/fnut.2019.00116. eCollection 2019. PubMed PMID: 31448279; PubMed Central PMCID: PMC6691186.
  9. *Gannon BM, Thakker V, Bonam VS, Haas JD, Bonam W, Finkelstein JL, Udipi SA, Mehta S. A Randomized Crossover Study to Evaluate Recipe Acceptability in Breastfeeding Mothers and Young Children in India Targeted for a Multiple Biofortified Food Crop Intervention. Food and Nutrition Bulletin2019 Jul 30;:379572119855588. doi: 10.1177/0379572119855588. [Epub ahead of print] PubMed PMID: 31359782.
  10. *Huey SL, Finkelstein JL, Venkatramanan S, Udipi SA, Ghugre P, Thakker V, Thorat A, Potdar RD, Chopra HV, Kurpad AV, Haas JD, Mehta S.Prevalence and Correlates of Undernutrition in Young Children Living in Urban Slums of Mumbai, India: A Cross Sectional Study. Frontiers in Public Health2019;7:191. doi: 10.3389/ fpubh.2019.00191. eCollection 2019. PubMed PMID: 31355176; PubMed Central PMCID: PMC6639755.
  11. **Wang R, Ongagna-Yhombi SY, Lu Z, Centeno-Tablante E, Colt S, Cao X, Ren Y, Cárdenas WB, Mehta S, Erickson D. Rapid Diagnostic Platform for Colorimetric Differential Detection of Dengue and Chikungunya Viral Infections. Analytical Chemistry2019 Apr 16;91(8):5415-5423. doi: 10.1021/acs.analchem.9b00704. Epub 2019 Mar 29. PubMed PMID: 30896928.
  12. *Srinivasan B, Finkelstein JL, O'Dell D, Erickson D, Mehta S. Rapid diagnostics for point-of-care quantification of soluble transferrin receptor. EBioMedicine2019 Apr;42:504-510. doi: 10.1016/ j.ebiom.2019.03.017. Epub 2019 Mar 16. PubMed PMID: 30885726; PubMed Central PMCID: PMC6491390.
  13. Finkelstein JL, Mehta S, Luna SV, Rahn M, Villapando V, Mundo V, Shamah-Levy T, Beebe SE, Haas JD. A Randomized Trial of Iron-Biofortified Beans in School Children in Mexico. Nutrients. 2019 Feb 12;11(2). PMID: 30759887. Joint first author.
  14. Finkelstein JL, Fothergill A*, Hackl LS, Haas JD, Mehta S. Iron biofortification interventions to improve iron status and functional outcomes. Proceedings of the Nutrition Society2019 Jan 30:1-11. PMID: 30698117.
  15. *Srinivasan B, O’Dell D, Finkelstein JL, Lee S, Erickson D, Mehta S. ironPhone: Mobile device coupled point-of-care diagnostics for assessment of iron status by quantification of serum ferritin. Biosensors & Bioelectronics. 2018 Jan 15;99:115-121. doi: 10.1016/j.bios.2017.07.038. PubMed PMID: 28750335.
  16. Stewart-Ibarra AM, Ryan SJ, Kenneson A, King CA, Abbott M, Barbachano-Guerrero, Beltrán-Ayala E, Borbor-Cordova MJ, Cárdenas WB, Cueva C, Finkelstein JL, Lupone CD, Jarman RG, Berry IM, Mehta S, Polhemus M, Silva M, Endy TP. The burden of dengue fever and chikungunya in southern coastal Ecuador: Epidemiology, clinical presentation, and phylogenetics from the first two years of a prospective study. American Journal of Tropical Medicine and Hygiene.2018 May 98(5):1444-1459. doi:10.4269/ajtmh.17-0762.
  17. *Yu EA, Hu PJ, Metha S. Plasma fatty acids in de novo lipogenesis pathway are associated with diabetogenic indicators among adults: NHANES 2003–2004. American Journal of Clinical Nutrition.2018 Sep 108(3):622-632. https://doi.org/10.1093/ajcn/nqy165.
  18. *Huey SL, Venkatramanan S, Udipi SA, Finkelstein JL, Ghugre P, Haas JD, Thakker V, Thorat A, Salvi A, Kurpad AV, Mehta S. Corrigendum: Acceptability of iron- and zinc-biofortified pearl millet (ICTP-8203)-based complementary foods among children in an urban slum of Mumbai, India. Frontiers in Nutrition18Oct2018. https://doi.org/10.3389/fnut.2018.00092 (correction article of doi: 10.3389/fnut.2017.00039 [2017])
  19. Finkelstein JL, Herman HS, Guetterman, HM, Peña-Rosas, J-P, Mehta, S. Daily iron supplementation for prevention or treatment of iron deficiency anaemia in infants, children, and adolescents. Cochrane Database of Systematic Reviews2018 Dec Issue 12 Art. No.: CD013227. DOI: 10.1002/14651858.cd013227.
  20. **Lu Z, Rey E, Vemulapati S, Srinivasan B, Mehta S, Erickson D. High-yield paper-based quantitative blood separation system. Lab on a Chip. 2018 Dec 24:3865-3871. http://dx.doi.org/10.1039/C8LC00717A 
  21. **Lu Z, O’Dell D, Srinivasan B, Rey E, Wang R, Vemulapati S, Mehta S, Erickson D. Rapid diagnostic testing platform for iron and vitamin A deficiency. Proc Natl Acad Sci USA. 2017 Dec. 19;114(51):13513-13518. doi: 10.1073/pnas.1711464114. PubMed PMID: 29203653; PubMedmCentral PMCID: PMC5754775.
  22. Park H, Wood MR, Malysheva OV, Jones S, Mehta S, Brannon PM, Caudill MA. Placental vitamin D metabolism and its associations with circulating vitamin D metabolites in pregnant women. Am J Clin Nutr. 2017 Dec;106(6):1439-1448. doi: 10.3945/ajcn.117.153429. PubMed PMID: 29021285; PubMed Central PMCID: PMC5698837.
  23. Mehta S, Finkelstein JL, Venkatramanan S, Huey SL, Udipi SA, Ghugre P, Ruth C, Canfield RL, Kurpad AV, Potdar RD, Haas JD. Effect of iron and zinc-biofortified pearl millet consumption on growth and immune competence in children aged 12-18 months in India: Study protocol for a randomised controlled trial. BMJ Open. 2017 Nov 14;7(11):e017631. doi: 10.1136/bmjopen-2017-017631. Erratum in: BMJ Open. 2018 Jan 9;8(1):e017631corr1. PubMed PMID: 29138201; PubMed Central PMCID: PMC5695508.
  24. **Vemulapati S, Rey E, O'Dell D, Mehta S, Erickson D. A. Quantitative point-of-need assay for the assessment of vitamin D3 deficiency. Sci Rep. 2017 Oct 26;7(1):14142. doi: 10.1038/s41598-017- 13044-5. PubMed PMID: 29074843; PubMed Central PMCID: PMC5658325.
  25. *Purswani JM, Gala P, Dwarkanath P, Larkin HM, Kurpad A, Mehta S. The role of vitamin D in preeclampsia: A systematic review. BMC Pregnancy Childbirth. 2017 Jul 15;17(1):231. doi: 10.1186/s12884-017-1408-3. PubMed PMID: 28709403; PubMed Central PMCID: PMC5513133.
  26. Natamba BK, Mehta S, Achan J, Stoltzfus RJ, Griffiths JK, Young SL. The association between food insecurity and depressive symptoms severity among pregnant women differs by social support category: A cross-sectional study. Matern Child Nutr.2017 Jul;13(3). doi: 10.1111/mcn.12351. PubMed PMID: 27507230.
  27. Mehta S, Colt S, Lee S, Erickson D. Rainer Gross Award Lecture 2016: A laboratory in your pocket: Enabling precision nutrition. Food Nutr Bull.2017 Jun;38(2):140-145. doi:10.1177/0379572117709157. PubMed PMID: 28513261.
  28. *Wood MR, Yu EA, Mehta S. The human microbiome in the fight against tuberculosis. Am J Trop Med Hyg. 2017 Jun;96(6):1274-1284. doi: 10.4269/ajtmh.16-0581. Review. PubMed PMID:28719264; PubMed Central PMCID: PMC5462560.
  29. **Rey EG, O’Dell D, Mehta S, Erickson D. Mitigating the hook effect in lateral flow sandwich immunoassays using real-time reaction kinetics.Anal Chem. 2017 May 2;89(9):5095-5100. doi:10.1021/acs.analchem.7b00638. PubMed PMID: 28388030.
  30. *Colt S, Garcia-Casal MN, Peña-Rosas JP, Finkelstein JL, Rayco-Solon P, Weise Prinzo ZC, Mehta S. Transmission of Zika virus through breast milk and other breastfeeding-related bodily-fluids: A systematic review.PLoS Negl Trop Dis. 2017 Apr 10;11(4):e0005528. doi:10.1371/journal.pntd.0005528. eCollection 2017 Apr. Review. PubMed PMID: 28394887; PubMed Central PMCID: PMC5398716.
  31. De Steur H, Mehta S, Gellynck X, Finkelstein JL. GM biofortified crops: Potential effects on targeting the micronutrient intake gap in human populations. Curr Opin Biotechnol. 2017 Apr;44:181-188. doi:10.1016/j.copbio.2017.02.003. Review. PubMed PMID: 28288329.
  32. Boy E, Haas JD, Petry N, Cercamondi CI, Gahutu JB, Mehta S, Finkelstein JL, Hurrell RF. Efficacy of iron-biofortified crops. African Journal of Food, Agriculture, Nutrition and Development.AFRICAN SCHOLARLY SCIENCE COMMUNICATIONS TRUST (ASSCAT); 2017;17(2):11879–11892–11892. doi: 10.18697/ajfand.78.HarvestPlus03
  33. Stover PJ, Mehta S. Editorial overview: Food biotechnology. Curr Opin Biotechnol. 2017 Apr;44:v-vi.doi: 10.1016/j.copbio.2017.03.015. PubMed PMID: 28347578.
  34. Finkelstein JL, Haas JD, Mehta S. Iron-biofortified staple food crops for improving iron status: A review of the current evidence. Curr Opin Biotechnol. 2017 Apr;44:138-145. doi: 10.1016/j.copbio.2017.01.003. Epub 2017 Jan 25. Review. PubMed PMID: 28131049; PubMed Central PMCID: PMC5418367.
  35. *Srinivasan B, Lee S, Erickson D, Mehta S. Precision nutrition - review of methods for point-of-care assessment of nutritional status. Curr Opin Biotechnol. 2017 Apr;44:103-108. doi:10.1016/j.copbio.2016.12.001. Review. PubMed PMID: 28043002.
  36. Park H, Brannon PM, West AA, Yan J, Jiang X, Perry CA, Malysheva O, Mehta S, Caudill MA. Maternal vitamin D biomarkers are associated with maternal and fetal bone turnover among pregnant women consuming controlled amounts of vitamin D, calcium, and phosphorus. Bone. 2017 Feb;95:183-191. doi: 10.1016/j.bone.2016.12.002. PubMed PMID: 27939956; PubMed Central PMCID: PMC5222782.
  37. *Yu EA, John SH, Tablante EC, King CA, Kenneth J, Russell DG, Mehta S. Host transcriptional responses following ex vivo re-challenge with Mycobacterium tuberculosis vary with disease status. PLoS One.2017 Oct 4;12(10):e0185640. doi: 10.1371/journal.pone.0185640. eCollection 2017. PubMed PMID: 28977039; PubMed Central PMCID: PMC5627917.
  38. *Huey SL, Venkatramanan S, Udipi SA, Finkelstein JL, Ghugre P, Haas JD, Thakker V, Thorat A, Salvi A, Kurpad AV, Mehta S. Acceptability of Iron- and Zinc-Biofortified Pearl Millet (ICTP-8203)-Based Complementary Foods among Children in an Urban Slum of Mumbai, India. Front Nutr.2017 Aug 25;4:39. doi: 10.3389/fnut.2017.00039. eCollection 2017. PubMed PMID: 28971097; PubMed Central PMCID: PMC5609630.
  39. Toko EN, Sumba OP, Daud II, Ogolla S, Majiwa M, Krisher JT, Ouma C, Dent AE, Rochford R, Mehta S. Maternal vitamin D status and adverse birth outcomes in children from rural Western Kenya. Nutrients. 2016 Dec 7;8(12). pii: E794. PubMed PMID: 27941597; PubMed Central PMCID: PMC5188449.
  40. **Lee S, Mehta S, Erickson D. Two-color lateral flow assay for multiplex detection of causative agents behind acute febrile illnesses. Anal Chem. 2016 Sep 6;88(17):8359-63. doi:10.1021/acs.analchem.6b01828. PubMed PMID: 27490379; PubMed Central PMCID: PMC5396465.
  41. Park H, Brannon PM, West AA, Yan J, Jiang X, Perry CA, Malysheva OV, Mehta S, Caudill MA. Vitamin D metabolism varies among women in different reproductive states consuming the same intakes of vitamin D and related nutrients.J Nutr.2016 Aug;146(8):1537-45. doi:10.3945/jn.116.229971. PubMed PMID: 27335139; PubMed Central PMCID: PMC4958290.
  42. **Lee S, Srinivasan B, Vemulapati S, Mehta S, Erickson D. Personalized nutrition diagnostics at the point-of-need. Lab Chip. 2016 Jul 7;16(13):2408-17. doi: 10.1039/c6lc00393a. PubMed PMID:27272753.
  43. Herman HS, Mehta S, Cárdenas WB, Stewart-Ibarra AM, Finkelstein JL. Micronutrients and leptospirosis: A review of the current evidence.PLoS Negl Trop Dis. 2016 Jul 7;10(7):e0004652. doi: 10.1371/journal.pntd.0004652. eCollection 2016 Jul. Review. PubMed PMID: 27387046; PubMed Central PMCID: PMC4936698.
  44. **Lee S, O'Dell D, Hohenstein J, Colt S, Mehta S, Erickson D. NutriPhone: A mobile platform for low-cost point-of-care quantification of vitamin B12 concentrations. Sci Rep. 2016 Jun 15;6:28237. doi:10.1038/srep28237. PubMed PMID: 27301282; PubMed Central PMCID: PMC4908584.
  45. *Huey SL, Mehta S. Stunting: The need for application of advances in technology to understand a complex health problem. EBioMedicine. 2016 Apr;6:26-27. doi: 10.1016/j.ebiom.2016.03.013. PubMed PMID: 27211543; PubMed Central PMCID: PMC4856790.
  46. Murphy RA, Yu EA, Ciappio ED, Mehta S, McBurney MI. Suboptimal plasma long chain n?3 concentrations are common among adults in the United States, NHANES 2003-2004. Nutrients. 2015 Dec 9;7(12):10282-9. PMID: 26690213 PMCID: PMC4690086.
  47. Serina P, Riley I, Stewart A, Flaxman AD, Lozano R, Mooney MD, Luning R, Hernandez B, Black R, Ahuja R, Alam N, Alam SS, Ali SM, Atkinson C, Baqui AH, Chowdhury HR, Dandona L, Dandona R, Dantzer E, Darmstadt GL, Das V, Dhingra U, Dutta A, Fawzi W, Freeman M, Gamage S, Gomez S, Hensman D, James SL, Joshi R, Kalter HD, Kumar A, Kumar V, Lucero M, Mehta S, Neal B, Ohno SL, Phillips D, Pierce K, Prasad R, Praveen D, Premji Z, Ramirez-Villalobos D, Rampatige R, Remolador H, Romero M, Said M, Sanvictores D, Sazawal S, Streatfield PK, Tallo V, Vadhatpour A, Wijesekara N, Murray CJ, Lopez AD. A shortened verbal autopsy instrument for use in routine mortality surveillance systems. BMC Med.2015 Dec 16;13:302. PMID: 26670275 PMCID: PMC4681088.
  48. Serina P, Riley I, Stewart A, James SL, Flaxman AD, Lozano R, Hernandez B, Mooney MD, Luning R, Black R, Ahuja R, Alam N, Alam SS, Ali SM, Atkinson C, Baqui AH, Chowdhury HR, Dandona L, Dandona R, Dantzer E, Darmstadt GL, Das V, Dhingra U, Dutta A, Fawzi W, Freeman M, Gomez S, Gouda HN, Joshi R, Kalter HD, Kumar A, Kumar V, Lucero M, Maraga S, Mehta S, Neal B, Ohno SL, Phillips D, Pierce K, Prasad R, Praveen D, Premji Z, Ramirez-Villalobos D, Rarau P, Remolador H, Romero M, Said M, Sanvictores D, Sazawal S, Streatfield PK, Tallo V, Vadhatpour A, Vano M, Murray CJ, Lopez AD. Improving Performance of the tariff method for assigning causes of death to verbal autopsies. BMC Med. 2015;13(1):291. PMID: 26644140 PMCID: PMC4672473.
  49. Mehta S, Yu EA, Ahamed SF, Bonam W, Kenneth J. Rifampin resistance and diabetes mellitus in a cross-sectional study of adult patients in rural South India. BMC Inf Dis.2015;15(1):451. PMID: 26496855 PMCID: PMC4620627.
  50. Ogolla S, Daud I, Asito A, Sumba O, Ouma C, Vulule J, Middeldorp J, Dent A, Mehta S, Rochford R. Reduced transplacental transfer of Epstein-Barr virus specific maternal antibodies to neonates of mothers with Plasmodium falciparum malaria infection during pregnancy. Clin Vaccine Immunol.2015 Nov;22(11):1197–205. PMID: 26376931 PMCID: PMC4622112.
  51. McBurney MI, Yu EA, Ciappio ED, Bird JK, Eggersdorfer M, Mehta S. Suboptimal serum α-tocopherol concentrations observed among younger adults and those depending exclusively upon food sources, NHANES 2003-2006. PLoS One2015;10:e0135510. PMID: 26287975 PMCID: PMC4546010.
  52. Finkelstein JL, Mehta S, Udipi SA, Ghugre PS, Luna SV, Wenger MJ, Murray-Kolb LE, Przybyszewski EM, Haas JD.A randomized trial of iron-biofortified pearl millet in school children in India. J Nutr. 2015. PMID:25948782 Jul;145(7):1576–81. Joint first author.
  53. Finkelstein JL, Gala P, Rochford R, Glesby MJ, Mehta S. HIV/AIDS and lipodystrophy: Implications for clinical management in resource-limited settings. J Int AIDS Soc.2015 Jan 15;18(1):19033. PMID: 25598476.
  54. Natamba BK, Achan J, Arbach A, Oyok TO, Ghosh S, Mehta S, Stoltzfus RJ, et al. Reliability and validity of the center for epidemiologic studies-depression scale in screening for depression among HIV-infected and -uninfected pregnant women attending antenatal services in northern Uganda: A cross-sectional study. BMC Psychiatry. 2014 Nov 22;14(1):303. PMCID: PMC4260190.
  55. Erickson D, O’Dell D, Jiang L, Oncescu V, Gumus A, Lee S, Mancuso M, Mehta S. Smartphone technology can be transformative to the deployment of lab-on-chip diagnostics. Lab Chip2014;14:3159-64. PMCID: PMC4117816.
  56. *Ahmed S, Finkelstein JL, Stewart AM, Kenneth J, Polhemus ME, Endy TP, Cardenas W, Mehta S. Micronutrients and dengue: A review of the current evidence. Am J Trop Med Hyg2014;91(5):1049-56. PMCID: PMC4228873.
  57. Lee S, Oncescu V, Mancuso M, Mehta S, Erickson D. A smartphone platform for the quantification of vitamin D levels. Lab Chip2014;14:1437-42. PMID: 24569647.
  58. Murray CJ, Lozano R, Flaxman AD, Serina P, Phillips D, Stewart A, James SL, Vahdatpour A, Atkinson C, Freeman MK, Ohno SL, Black R, Ali SM, Baqui AH, Dandona L, Dantzer E, Darmstadt GL, Das V, Dhingra U, Dutta A, Fawzi W, Gómez S, Hernández B, Joshi R, Kalter HD, Kumar A, Kumar V, Lucero M, Mehta S, Neal B, Praveen D, Premji Z, Ramírez-Villalobos D, Remolador H, Riley I, Romero M, Said M, Sanvictores D, Sazawal S, Tallo V, Lopez AD. Using verbal autopsy to measure causes of death: The comparative performance of existing methods. BMC Med2014;12:5. PMCID: PMC3891983.
  59. Mehta S, Mugusi FM, Bosch RJ, Aboud S, Urassa W, Villamor E, Fawzi WW. Vitamin D status and TB treatment outcomes in adult patients in Tanzania. BMJ Open2013;3:e003703. PMCID: PMC3840339.
  60. Fataki M, Kisenge RR, Sudfeld CR, Aboud S, Okuma J, Mehta S, Spiegelman D, Fawzi WW. Effect of zinc supplementation on duration of hospitalization in Tanzanian children presenting with acute pneumonia. J Trop Pediatr2014;60:104-11. PMCID: PMC3967446.
  61. Hawkins C, Christian B, Ye J, Nagu T, Aris E, Chalamilla G, Spiegelman D, Mugusi F, Mehta S, Fawzi W. Prevalence of hepatitis B co-infection and response to antiretroviral therapy among HIVinfected patients in urban Tanzania. AIDS2013;27:919-27. PMID: 23196935.
  62. Finkelstein JL, Manji KP, Duggan C, Hertzmark E, Mehta S, Msamanga GI, Spiegelman D, Fawzi WW. Predictors of incident tuberculosis in HIV-exposed children in Tanzania. East Afr Med J2012;89:183-192.
  63. Finkelstein JL, Mehta S, Duggan CP, Manji KP, Mugusi FM, Aboud S, Spiegelman D, Msamanga GI, Fawzi WW. Maternal vitamin D status and child morbidity, anemia, and growth in human immunodeficiency virus-exposed children in Tanzania. Pediatr Infect Dis J 2012;31:171-175. PMCID: PMC3813463.
  64. Shet A, Arumugam K, Rajagopalan N, Dinakar C, Krishnamurthy S, Mehta S, Shet AS. The prevalence and etiology of anemia among HIV-infected children in India. Eur J Pediatr. 2012;171:531-540. PMID: 22009132.
  65. Finkelstein JL, Mehta S, Aboud S, Duggan CP, Kupka R, Spiegelman D, Msamanga GI, Fawzi WW. Predictors of anemia and iron deficiency in HIV-infected pregnant women: A potential role for vitamin D and parasitic infections. Public Health Nutr2012;15:928-937. PMCID: PMC3366262.
  66. Mehta S, Mugusi FM, Bosch RJ, Aboud S, Chatterjee A, Finkelstein JL, Fataki M, Kisenge R, Fawzi WW. A randomized trial of multivitamin supplementation in children with tuberculosis in Tanzania. Nutr J2011;10:120. PMCID: PMC3229564.
  67. Mehta S, Mugusi FM, Spiegelman D, Villamor E, Finkelstein JL, Hertzmark E, Giovannucci EL, Msamanga GI, Fawzi WW. Vitamin D status and its association with morbidity including wasting and opportunistic illnesses in HIV-infected women in Tanzania. AIDS Patient Care STDs2011;25:579-585. PMCID: PMC3183700.
  68. Murray CJ, Lopez AD, Black R, Ahuja R, Mohd Ali S, Baqui A, Dandona L, Dantzer E, Das V, Dhingra U, Dutta A, Fawzi W, Flaxman AD, Gomez S, Hernandez B, Joshi R, Kalter H, Kumar A, Kumar V, Lozano R, Lucero M, Mehta S, Neal B, Ohno SL, Prasad R, Praveen D, Premji Z, Ramirez-Villalobos D, Remolador H, Riley I, Romero M, Said M, Sanvictores D, Sazawal S, Tallo V. Population Health Metrics Research Consortium Gold Standard Verbal Autopsy Validation Study: Design, implementation and development of analysis datasets. Popul Health Metr2011;9:27. PMCID: PMC3160920.
  69. Liu E, Spiegelman D, Semu H, Hawkins C, Chalamilla G, Aveika A, Nyamsangia S, Mehta S, Mtasiwa D, Fawzi WW. Nutritional status and mortality among HIV-infected patients receiving antiretroviral therapy in Tanzania. J Infect Dis2011; 204:282-90. PMID: 21673040.
  70. Mehta S, Fawzi WW. Editorial commentary: Micronutrient supplementation as adjunct treatment in HIV-infected patients. Clin Inf Dis. 2010;50:1661-1663. PMID: 20455704.
  71. Mehta S, Spiegelman D, Aboud S, Giovannucci EL, Msamanga GI, Hertzmark E, Mugusi FM, Hunter DJ, Fawzi WW. Lipid-soluble vitamins A, D, and E in HIV-infected pregnant women in Tanzania. Eur J Clin Nutr. 2010;64:808-17. PMCID: PMC3078753.
  72. Mehta S, Giovannucci E, Mugusi FM, Spiegelman D, Aboud S, Hertzmark E, Msamanga GI, Hunter D, Fawzi WW. Vitamin D status of HIV-infected women and its association with HIV disease progression, anemia, and mortality. PLoS One2010;5:e8770. PMCID: PMC2808247.
  73. Franke MF, Spiegelman D, Ezeamama A, Aboud S, Msamanga GI, Mehta S, Fawzi WW. Malaria parasitemia and CD4 T-cell count, viral load, and adverse HIV outcomes among HIV-infected pregnant women in Tanzania. Am J Trop Med Hyg2010;82:556-562. PMCID: PMC2844563.
  74. Mugusi FM, Mehta S, Villamor EV, Urassa W, Saathoff E, Bosch RJ, Fawzi WW. Factors associated with mortality in HIV-infected and uninfected patients with pulmonary tuberculosis. BMC Public Health2009;9:409. PMCID: PMC2779816.
  75. Mehta S, Hunter DJ, Mugusi FM, Spiegelman D, Manji KP, Giovannucci EL, Hertzmark E, Msamanga GI, Fawzi WW. Perinatal outcomes, including mother-to-child transmission of HIV, and child mortality, and their association with maternal vitamin D status in Tanzania. J Inf Dis2009;200:1022-1030. Accompanied by an Editorial commentary: Spector SA. Vitamin D earns more than a passing grade. J Inf Dis2009;200:1015-1017. PMCID: PMC2758703.
  76. Shet A, Mehta S, Rajagopalan N, Dinakar C, Ramesh E, Samuel NM, Indumathi CK, Fawzi WW, Kurpad AV. Anemia and growth failure among HIV-infected children in India: A retrospective analysis. BMC Pediatr2009;9:37. PMCID: PMC2702283.
  77. Mehta S, Manji KP, Young AM, Brown ER, Chasela CC, Taha TE, Read JS, Goldenberg RL, Fawzi, WW. Nutritional indicators of adverse pregnancy outcomes and mother-to-child transmission of HIV among HIV-infected women. Am J Clin Nutr2008;87:1639-49. PMCID: PMC2474657.
  78. Wig N, Sakhuja A, Agarwal SK, Khakha DC, Mehta S, Vajpayee M. Multidimensional health status of HIV-infected outpatients at a tertiary care center in north India. Indian J Med Sci2008;62:87-97. PMID: 18376081
  79. Mehta S, Ding EL, Fawzi WW, Giovannucci EL. Influence of estrogen therapy on effects of calcium and vitamin D for colorectal cancer prevention. Int J Cancer2008;122:1690-4. PMID: 18092326. Joint first author.
  80. Mehta S, Fawzi W. Effects of vitamins, including vitamin A, on HIV/AIDS patients. Vitam Horm 2007; 75: 355-383. PMID: 17368322.
  81. Sohal DPS, Garg N, Singh D, Mehta S, Anand K, Kapoor SK. Antibiotic prescription practice at primary and secondary level hospitals of a medical college. Indian Practitioner2006;59(12):789-94.

 

Book

Mehta S, Finkelstein JL, eds. 2018. Nutrition and HIV: Epidemiologic Evidence to Public Health Practice. Boca Raton, FL: CRC Press. (Invited book)

 

Book Chapters

1. Huey SL, Mehta S. Human immunodeficiency virus and vitamin A. In Mehta S, Finkelstein JL, eds., Nutrition and HIV: Epidemiologic Evidence to Public Health Practice, 1-26. Boca Raton, FL: CRC Press, 2018. 

2. Yu EA, Mehta S. Vitamin D and HIV. In Mehta S, Finkelstein JL, eds., Nutrition and HIV: Epidemiologic Evidence to Public Health Practice, 153-189. Boca Raton, FL: CRC Press, 2018. 

3. Wilkinson, AL, Huey, SL, Mehta, S. Antioxidants and HIV/AIDS: Zinc, selenium, and vitamins C and E. In Mehta S, Finkelstein JL, eds., Nutrition and HIV: Epidemiologic Evidence to Public Health Practice, 191-205. Boca Raton, FL: CRC Press, 2018. 

4. Finkelstein JL, Mehta S. Micronutrients and perinatal outcomes in HIV-infected pregnant women. In Mehta S, Finkelstein JL, eds., Nutrition and HIV: Epidemiologic Evidence to Public Health Practice, 207-242. Boca Raton, FL: CRC Press, 2018. 

5. Finkelstein JL, Aribindi H, Herman HS, Mehta S. Micronutrients and HIV in pediatric populations. In Mehta S, Finkelstein JL, eds., Nutrition and HIV: Epidemiologic Evidence to Public Health Practice, 275-305. Boca Raton, FL: CRC Press, 2018. 

6. Yu EA, Finkelstein JL, Mehta S. HIV and micronutrients. Editors: Pammi M, Vallejo JG, Abrams SA. Nutrition-Infection Interactions and Impacts on Human Health,2014. Boca Raton, FL: Taylor and Francis Books, Inc.

7. Finkelstein JL, Mugusi FM, Mehta S, Fawzi WW. HIV/AIDS and nutrition in the HAART era: Programmatic implications for HIV/AIDS care and treatment in resource-limited settings. Editors: Marlink RG, Teitelman SJ. From the Ground Up: Building Comprehensive HIV/AIDS Care in Resource-Limited Settings2009, Washington, DC: Elizabeth Glaser Pediatric AIDS Foundation.

8. Mehta S, Finkelstein JL, Fawzi WW. Micronutrient status and pregnancy outcomes in HIV-infected women. Editors: Lammi-Keefe CJ, Couch SC, Philipson, E. Handbook of Nutrition and Pregnancy, 2008; 23: 355-365. Baton Rouge, LA: Humana Press.

9. Mehta S, Finkelstein JL, Fawzi WW. Nutritional interventions in HIV-infected breastfeeding women. Ann Nestlé[Engl] 2007; 65: 39–48.

 

Technical and Working Papers 

1. Berry J, Mehta S, Mukherjee P, Ruebeck H, Shastry GK. Implementation and effects of India’s National School-Based Iron Supplementation Program. 2018 Aug. Wellesley College, Wellesley, MA.

2. Berry J, Mehta S, Mukherjee P, Ruebeck H, Shastry GK. Inputs, monitoring, and crowd-out in school-based health interventions: Evidence from India’s Midday Meals Program. 2018 Aug. Wellesley College, Wellesley, MA.

3. **Ruth C, Yu EA, Huey SL, Chitkushev L, Mehta S, Zhang GL. ConnEDCT: A development framework for mobile electronic data capture in disconnected communities. computer science and education in computer science 1:233-247. https://www.ceeol.com/search/article-detail?id=529703

4. Mehta S, Yu EA. Nutrition and tuberculosis: A manual for health professionals. In review at the WHO.

5. Mehta S, Fawzi WW. Hunger and HIV and tuberculosis. Technical paper for the World Hunger Series 2007. World Food Programme, Rome, Italy.

 

Cochrane Protocols and World Health Organization Reviews in Progress

1. Review: Huey SL, Acharya N, Silver A, Sheni R, Yu EA, Peña-Rosas JP, Mehta S. The effects of oral vitamin D supplementation on linear growth and non-communicable diseases among infants and children younger than five years of age. Cochrane Developmental, Psychosocial and Learning Problems Group, editor. Submitted.

2. Protocol: Gannon BM, Colt S, Rogers LM, Garcia-Casal MN, Martinez RX, Lopez-Perez L, Ghezzi-Kopel K, Mehta S. Biomarkers for assessing vitamin A deficiency in populations. Cochrane Infectious Diseases Group, editor. In review.

 

Lead Instructor

NS 3060 - Nutrition and Global Health

This course introduces students to nutritional problems in the global community, through evaluation of the scientific literature and exploration of epidemiological, biological, demographic, and social factors that affect nutritional status. Students are encouraged to think critically about the major challenges to improve nutrition with applications to infectious diseases, maternal and child health, and noncommunicable diseases. Students have an opportunity to develop interventions to target a nutritional problem in the context of a specific country.

NS 6580 - Advanced Epidemiology: Theory and Practice

This course uses a combination of lectures and discussions with “hands-on” laboratory sessions as a method to learn about nutritional epidemiology. Students should be able to apply the methods learned in this class and gain proficiency in designing, conducting, and analyzing nutritional epidemiology studies. Broadly, the topics covered will guide the design of research projects and include data management and data analysis, as it pertains to nutritional data, measurement errors in nutrition assessment, biomarkers of nutritional status or outcome, methods of energy adjustment, anthropometry, and body composition, CDC and WHO growth charts, propensity scores, genetics and gene-environment interactions in nutritional epidemiology, measurement and analysis of physical activity, translating conceptual models into statistical models and dealing with confounders, mediators, endogenous variables, and multilevel models, working with large samples, and longitudinal analysis for analyzing the relationship between diet and disease. 

 

Core Faculty 

PAHO/WHO/Cochrane/Cornell Summer Institute in Systematic Reviews for Global PolicyMaking 

 

M.B.B.S. (Bachelor of Medicine and Bachelor of Surgery) - All India Institute of Medical Sciences, New Delhi, India - 2003 

M.S. (Epidemiology) - Harvard University, Cambridge MA - 2004 

Sc.D. (Epidemiology and Nutrition) - Harvard University, Cambridge MA - 2009 

Middle States Accreditation Committee - Subcomittee on Ethics and Integrity, Office of the Vice Provost for Research, Cornell University

Member, Institutional Review Board, Cornell University

Faculty Advisory Board for Information Technology, College of Human Ecology, Cornell University

IT Security Advisory Council, College of Agriculture and Life Sciences, Cornell University

Member, Search Committee, Director, DNS

Member, Search Committee, Executive Director, DNS

 

Mehta Research Group

mehta.human.cornell.edu 

 

Insight: Institute for Nutritional Sciences, Global Health and Technology

insight.cornell.edu

twitter.com/MehtaRG 

twitter.com/INSiGHTCornell

 

View all people