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Marie

Caudill

Professor
Division of Nutritional Sciences
NS CALS
Office

228 Savage Hall

Phone

Biography

Professor Caudill is internationally recognized for her work on folate and choline, and the intake levels required to meet metabolic requirements and improve physiological outcomes. She has published over 150 papers, reviews, and chapters in these areas, and is frequently an invited speaker on topics related to the importance of choline nutrition during pregnancy and lactation.  Professor Caudill is also a co-editor on the popular graduate level nutrition textbook "Biochemical, Physiological, & Molecular Aspects of Human Nutrition”.

Research Program

 

A primary goal of the Caudill laboratory is to generate data that will inform the development of nutrient intake recommendations that promote mother and child nutrition, health and well-being.  An integrative approach which includes targeted and non-targeted assessments of genomic, epigenetic, biochemical and physiologic endpoints is employed.

Current Research Activities

Impact of dietary choline and genetic variation on choline distribution during human pregnancy (Dr. Melissa McDougall, Dr. Kevin Klatt, Dr. Siraphat Taesuwan, Olga Malysheva, Aura Loinard, Dr. Devapatla and Dr. Vidavalur)  

Impact of maternal choline intake during pregnancy on DHA delivery to the developing fetus  (Dr. Melissa McDougall, Dr. Kevin Klatt, Dr. Siraphat Taesuwan, Dr. Bill Harris, Dr. Kristina Jackson, Dr. Tom Brenna, Dr. Devapatla and Dr. Vidavalur).

Influence of the gut microbiome on choline bioavailability (Dr. Melissa McDougall, Dr. Liz Johnson, Dr. Kevin Klatt, and Dr. Siraphat Taesuwan).

 

Professor Caudill has 145+ publications including 125 peer reviewed original research papers. Her CV provides a full list of her published work, and can be found at    https://www.human.cornell.edu/people/mac379

Publications in 2019 include:

  1. Julia H King, Sze Ting (Cecilia) Kwan, Jian Yan, Xinyin Jiang, Vladislav G Fomin, Samantha P Levine, Emily Wei, Mark S Roberson, and Marie A Caudill. Maternal choline supplementation modulates placental markers of inflammation, angiogenesis, and apoptosis in a mouse model of placental insufficiency. Nutrients 2019;11,374.
  2. Siraphat Taesuwan, Francoise Vermeylen, Patricia Cassano, Marie A. Caudill. Relationship of choline intake with blood pressure in the National Health and Nutrition Examination Survey 2007-10. Am J Clin Nutr. 2019 Mar 1;109(3):648-655
  3. Ayelet Hashahar Orenbuch, Keren Freide, Siraphat Taesuwan, Raz Yaffe, Marie A Caudill, Hava Miriam Golan. Prenatal nutritional intervention reduces autistic-like behavior rates among Mthfr-deficient mice. Frontiers in Neuroscience. In Press.
  4. John T Brosnan, Lesley Plumptre, Margaret E Brosnan, Theerawat Pongnopparat, Shannon P Masih, Carly E Visentin, Howard Berger, Yvonne Lamers, Marie A Caudill, Olga V Malysheva, Deborah L O’Connor, Young-In Kim. Formate concentrations in maternal plasma during pregnancy and in cord blood in a cohort of pregnant Canadian women: relationships to genetic polymorphisms and plasma metabolites. Am J Clin Nutr. 2019. In Press.
  5. Julia H King, Sze Ting (Cecilia) Kwan, Sajin Bae, Kevin C Klatt, Jian Yan, Olga V Malysheva, Xinyin Jiang, Mark S Roberson, and Marie A Caudill. Maternal choline supplementation alters vitamin B-12 status in human and murine pregnancy. Nutrition Research.  J Nutr Biochem. 2019. 72: In Press.
  6. Wallace TC; Blusztajn JK; Caudill MA; Klatt KC; Zeisel SH. Choline: The Neurocognitive Essential Nutrient of Interest to Obstetricians and Gynecologists. J Dietary Supplements. 2019, In Press.
  7. Korsmo H, Caudill MA, Jiang X. Choline: Exploring the Growing Science on Its Benefits for Moms and Babies. Nutrients. 2019, 11, 1823; doi:10.3390/nu11081823
  8. Kevin C. Klatt, Melissa Q McDougall, Olga V. Malysheva, J. Thomas Brenna, Mark S. Roberson, Marie A. Caudill. Reproductive state and choline intake influence enrichment of plasma lysophosphatidylcholine-DHA: a post-hoc analysis of a controlled-feeding trial. British Journal of Nutrition. In Press.
  9. Lesley Plumptre, Stephanie Tammen, Kyoung-Jin Sohn, Shannon P. Masih, Carly E. Visentin, Susanne Aufreiter, Olga Malysheva, Theresa H Schroder, Anna Ly, Howard Berger, Ruth Croxford, Yvonne Lamers, Marie A Caudill, Sang-Woon Choi, Deborah L O’Connor, Young-In Kim. Maternal and cord blood folate concentrations are inversely associated with fetal DNA hydroxymethylation, but not DNA methylation, in a cohort of pregnant Canadian women. J Nutr. 2019; In Press.
  10. Marta Cosín-Tomás, Yan Luan, Daniel Leclerc, Olga V. Maleysheva, Nidia Lauzon, Renata H. Bahous, Karen E. Christensen, Marie A. Caudill, Rima Rozen. Moderate folic acid supplementation in pregnant mice results in behavioral alterations in offspring, with sex-specific changes in methyl metabolism and cerebral cortex gene expression.  Submitted.

     

Invited Speaker, Nutrition During Pregnancy and Lactation: Exploring New Evidence – A Workshop for the The National Academies of Sciences, Engineering, and Medicine.  Washington DC. January 29th 2020.

Invited Speaker and Chair, Choline Awareness During the Perinatal Period: Gaining Momentum in the United States Yet Overlooked in Europe. European Gynecology Society Congress Vienna, Austria. October 18th 2019.

Invited Speaker, Choline Webinar for Medical Professionals, Live on MyCME.com.  Oct 15, 2019.

Invited Speaker, Shopping For Health Annual Conference, St. Louis, Missouri, July 14-16 2019.

Dietary Guidelines Advisory Committee (DGAC) Public Comments Session (2020).  Provided public comments to DGAC in an effort to raise awareness of the importance of adequate choline during the perinatal period. Washington, DC, July 11 2019.

 

 

 

 

 

Invited Speaker, Choline Webinar for Medical Professionals, Live on MyCME.com.  Oct 15, 2019.

Invited Speaker, Shopping For Health Annual Conference, St. Louis, Missouri, July 14-16 2019.

Dietary Guidelines Advisory Committee (DGAC) Public Comments Session (2020).  Provided public comments to DGAC in an effort to raise awareness of the importance of adequate choline during the perinatal period. Washington, DC, July 11 2019.

 

I taught Nutrition and Disease (NS 4410) from 2008-2018.  As of Spring 2019, I transitioned to Human Nutrition and Nutrient Metabolism (NS 3310). A top priority for me in my teaching and advising is to convey respect for the students and a sense that I care about their learning.

NS 3310 Human Nutrition and Nutrient Metabolism (4 credit units). Organized in a lecture format with opportunities for engaged learning, this course facilitates the students’ integration of biochemistry and physiology in the context of nutrient metabolism, and strives to ensure that students will have a working knowledge of the sources, metabolism and function of each essential nutrient.

BA, 1990, Physical Education (Summa Cum Laude), College of Education, University of North Florida, Jacksonville, FL;

BS, 1992, Health Science (Summa Cum Laude), College of Health, University of North Florida, Jacksonville, FL;

MS, 1993, Health Science, College of Health, University of North Florida, Jacksonville, FL;

PhD, 1997, Nutritional Sciences, Food Science and Human Nutrition, College of Agriculture, University of Florida, Gainesville, FL (Lynn Bailey, Thesis Advisor);

Additional Training Registered Dietitian, 1994, Dietetic Internship at Emory University Hospital, Atlanta, GA.

University Committees

HE Representation on the University Tenure Appeals Panel, July 1 2017-June 30 2022

Stephen H. Weiss Fellows Selection Committee, July 1, 2016-June 30, 2019 (Chair in 2018 and 2019)

College Committees

Ad hoc review committee (CALS)

Department Committees

Curriculum Committee, 2017-2020, Cornell University

 

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