The Lujan laboratory investigates the link between nutrition, metabolism and fertility in women. Specific interests include elucidating the endocrine, cellular and molecular mechanisms that to lead amenorrhea (loss of regular menstrual cycles) in overweight and obese women as well as improving the diagnosis and treatment of polycystic ovary syndrome (PCOS) - a condition of impaired fertility that is tightly linked to insulin resistance and excess male hormone production.
Current Research Opportunities
We currently have openings for graduate students. Interested students should consult websites for the Graduate Fields of Nutritional Sciences ( NS) and/or Molecular and Integrative Physiology ( MIP).
We are always interested in hearing from highly motivated individuals interested in postdoctoral studies in the area of nutritional and metabolic regulation of reproductive function.
Candidates with experience working in the area of Infertility, Polycystic Ovary Syndrome and/or Obesity and Insulin Resistance are encouraged to email us their curriculum vitae and a statement of research interest.
The Lujan laboratory uses high-resolution serial ovarian ultrasonography to track changes in follicle development and to identify key periods during the menstrual cycle in which follicle development and ovulation are most sensitive to metabolic cues (e.g. energy balance, body composition, fat-derived hormones, glucose, insulin, androgens). Social science and epidemiology concepts are also incorporated in our research to further understanding on current lifestyle behaviors and beliefs in women with amenorrhea.
By examining the physiological and emotional health associated with amenorrhea, the goal of the Lujan laboratory is to develop nutritional, lifestyle and pharmaceutical regimens that promote and preserve reproductive health in women.