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The Stipanuk Lab

Welcome to the Stipanuk Lab of the Division of Nutritional Sciences at Cornell University

Studying mammalian cysteine metabolism


Intermediary metabolism of cysteine in mammalian tissues

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Hydrogen sulfide production and signaling in cysteine excess


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Studies in cysteine dioxygenase knockout  mice

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Structure-function studies of cysteie dioxygenase

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Regulation of cysteine dioxygenase concentration by degradation by the ubiquitin-proteasome system  

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Studying responses to amino acid deprivation

GCN2 (eIF2a kinase 4)-mediated responses
GCN2 cross-talk with mTOR
Integrated stress responses

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